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We use a genetic test devised by the Canadian company NUTRIGENOMIX to find out your unique nutritional needs and to individually tailor your diet to compensate for any genetic vulnerability you might have.

Q: What is nutrigenomics?

A: Nutrigenomics uses genetic testing to address issues important to nutrition and health. The protein products of our genes (enzymes, transporters, receptors, hormones etc.) interact with components of the food we eat to influence our nutritional status.

Q: What is the goal of nutrigenomics?

A: The main goal of nutrigenomics is to prevent chronic disease by examining how the interaction between genes and diet can positively influence human health. This interaction is specific to every individual because we all have different genes. Due to genetic variation, people differ in their nutritional needs and health outcomes.

Q: How does genetic variation affect someone’s health?

A:   Genetic variation leads to differences in the amount of proteins we produce and how efficiently proteins function. These proteins have key roles in our body, thus influencing our entire metabolism.

Q: How exactly do genes affect nutritional status or health status?

A: The products of our genes, called proteins, interact with the components of the food we eat to influence nutrition. Different versions of the same gene can produce slightly different proteins, which in turn may interact with dietary components in different ways. For example, differences may manifest in the absorption, metabolism, uptake and excretion of dietary components by the body. Certain gene variants may even predispose the individuals to adverse diet-related health effects and disease: someone may be prone to Vitamin C deficiency and increased risk of CVD, type 2 diabetes and cancer, while another might have a severely impaired ability to absorb folate in the diet, which predisposes to heart disease and strokes.

Q: Tell me more about Nutrigenomix and their genetic test.

A: Nutrigenomix Inc. is a University of Toronto start-up biotechnology company founded by global leaders in nutrigenomics research. Their 45-gene Health and Wellness test is a comprehensive genetic test that consists of a panel of 45 genetic markers that can help you identify your unique nutritional needs and exercise requirements. The results of this test can impact weight loss & body composition, nutrient metabolism, heart health, food intolerances, oxidative stress, inflammation, detoxifying ability and eating habits. The test also provides you with information related to the relationship between your genes and athletic performance & injury risk. Your test results are presented in a customised report, which includes dietary and physical activity recommendations based on your individual genetic profile.

 

45-gene-testQ: What scientific evidence is the genetic test based on?

A: The Nutrigenomix genetic test is  based on cutting-edge research and stringent standards of scientific evidence. As a registered nutritionist I have access to all the medical trials in the Nutrigenomix database. For more information, please contact me at myantioxidantclub@gmail.com

Alternatively, you can sample some medical reports below:

Drinking Coffee and Risk of Myocardial Infarction in People with the GA or AA variant of the CYP1A2 Gene

Omega-3 Deficiency and Risk of Cardiovascular Disease in People with the GT or TT Variant of the NOS3 Gene

Saturated Fat Intake and Risk of Diabetes, CVD and Obesity in People with the CC variant of the APOA2 Gene

Salt Intake and Risk of Hypertension in People with the GA or AA variant of the ACE gene

High Carbohydrate Intake and Risk of Type 2 Diabetes in People with the TT variant of the TCF7L2 Gene

Dietary Folate Needs Vary based on the MTHFR Genotype

Dietary Vitamin C Needs Vary depending on GSTT1 Genotype

Vitamin D Deficiency in People with the Risk Variants of the CYP2R1 and GC Genes

Vitamin D, Calcium Metabolism, Risk of Osteoporosis and the DBP Gene

Q: What does the Nutrigenomix genetic test consist of?

A: The Nutrigenomix genetic test consists of a saliva test. Collecting and preparing the saliva sample needed for the Nutrigenomix DNA analysis is a simple process.  Each Nutrigenomix test kit contains the following: • A pamphlet of detailed instructions, with pictures. • A collection tube preassembled, with a funnel lid. • A small cap to replace the funnel lid after the sample has been obtained. • A specimen bag for storage and shipping. The entire process takes a few minutes and the results are available within  2-3 weeks.
Q: How can I order a Nutrigenomix test kit?
A: The Nutrigenomix test kit is only available through registered nutritionists and healthcare providers. Contact nutritionist Dana Knight at myantioxidantclub@gmail.com to find out more and order your test.

 

Q: How accurate are my genetic test results?

A: The accuracy of the genetic test results is between 99.7-100%.

Q: How long do I have to follow the dietary recommendations?

A: Your test results are not intended to form a short-term “diet.” The information provided in your report, combined with the nutritional plan created by your nutritionist will empower you with knowledge so that you can make the dietary choices that suit your genetic makeup for life.

Q: Do I have to start taking supplements?

A: It is usually possible for a person to meet the recommendations through diet alone. However, in some circumstances, a supplement may be beneficial.

Q: Can my genetics change?

A: The sequence of your genes will not change throughout your life, and so you will not need to be retested for the specific gene variants included in this test kit. Still, dietary recommendations may change over your lifetime because you may have different nutritional needs at different life stages.

Q: Could this advice change with new research?

A: No, but as the science of nutrigenomics evolves and additional findings are made, some of the advice provided in your report may be further fine-tuned to improve our ability to predict how you respond to certain nutrients. The current nutrigenomics advice you are now receiving is already superior to the general, one-size-fits-all advice. However, even if let’s say  you were found not to have the risk variant for vitamin C deficiency, future studies might uncover a different variant that affects how your body uses this vitamin.

Q: Are my siblings, parents and children likely to have the same genetics and same dietary advice?

A: No. With the exception of identical twins, DNA differs among people, and so genetics-based dietary recommendations cannot be made for someone unless that particular individual’s DNA is tested.

 

Q: Who will have access to my genetic test results?

A: Only your nutritionist will be able to access your genetic test results. Your Nutrigenomix test kit is marked with a unique barcode, which is what the company will use at their facilities to analyse your sample. Only your nutritionist will be able to link your kit’s barcode to your personal information. Nutrigenomix uses the Secure Socket Layer (SSL) protocol to encrypt information that is transmitted over the Internet. This technology uses 256-bit encryption, which ensures that confidential information cannot be viewed, intercepted or altered. Genetic information will never be disclosed, except where required by law.

Q: Can I request that my sample be destroyed?

A: Nutrigenomix will store your barcoded, anonymised DNA sample so that you will have the opportunity to be tested for additional genetic variants as new discoveries are made and the science develops. Such tests will be provided at a reduced cost since saliva samples will not need to be re-collected. However, you may have your sample destroyed by sending a written request to your nutritionist, who will inform Nutrigenomix.

Q: If I have more questions after receiving my test results, can I contact my nutritionist again?

A: Yes, you just need to schedule a follow-up appointment with your nutritionist.

Q: If I lose my Personalized Nutrition Report, can I request a new one?

A: Yes. Just ask your dietitian, who should have a PDF version of your report that can be emailed to you or re-printed.

Q: How will eating according to my genes improve my health? What kinds of improvements will I see? How long will it take?

A: It is difficult to say exactly how long it will take, because each person will have a different personalised nutritional plan depending on his or her initial overall health. You may notice healthy changes in body weight, blood test results such as cholesterol and blood sugar levels, and energy levels. The greatest benefit that eating according to your genes can provide is arming you with robust information about what nutritional measures you can take to reduce the risk of developing adverse health conditions.

Q: I’m a very picky eater. Can my food preferences be taken into consideration?

A: Yes. Be sure to discuss your food likes and dislikes with your nutritionist, as well as any food allergies, restrictions or intolerances.

Q: Are there people who don’t have any of the risk variants?

A: Approximately 0.9% of the population will not have any of the risk variants in this panel.

Q: Does that mean they can eat and drink whatever they want?

A: While these individuals may consider themselves genetically lucky, they should still follow general dietary guidelines for good nutrition and health, since the nutrients covered in this report have been linked to other health outcomes. For example, not having the CC variant for APOA2 means the client is not at an increased risk of obesity with high saturated fat consumption, but they might still be vulnerable to some of the other adverse health effects of saturated fat, such as cardiovascular disease.

Q: What would the advice have been if I didn’t have a certain variant?

A: If an individual does not have a certain risk variant, the advice for any dietary component is the recommendation set by official government-sanctioned health organisations. For the person with the risk variant, meeting the recommendation for that specific dietary component should be a top priority.

Q: Are my results unusual? How do I compare to the general population?

A: The majority of individuals would possess a combination of risk and non-risk variants. While the proportion of the population with the risk variant may differ in other ethnic groups, less than 0.2% of the population would be expected to carry a risk variant for all seven genes and approximately 0.9% of the population would be expected to carry the non-risk variant for all seven genes.

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